Pathogen fitness landscapes change when transmission cycles establish in non-native
environments or spill over into new vectors and hosts. The introduction of Leishmania
infantum in the Americas into the Neotropics during European colonization represents a
unique case study to investigate the mechanisms of ecological adaptation of this important
parasite. Defining the evolutionary trajectories that drive L. infantum fitness in this new
environment are of great public health importance as they will allow unique insight into …